H2S --> sulfite and advances in understanding H2S metabolism

One of the points in my hypotheses about why molybdenum is helping people with nausea and migraines (and apparently "morning sickness," though I have fewer pregnant friends than friends with migraines) is that the molybdenum is enabling higher activity of the sulfite oxidase enzyme--which uses a molybdenum cofactor--in transforming toxic sulfite to excretable sulfate. But where is the sulfite coming from? I think it's a metabolic product of hydrogen sulfide (H2S), which it turns out is important to making new blood vessels from existing ones (angiogenesis), vasodilation, and even keeping uterine muscles from contracting.

The pathways by which H2S is broken down in the body are still being clarified by researchers. Sulfite is often an end result, but sulfite is also used by the catabolism. Therefore, whether there is a net increase in sulfite from H2S catabolism is far from a given. A study published this past year by some Polish* researchers found that there appears to be a non-canonical pathway by which H2S is oxidized in the brain, and that pathway appears to use neuroglobin. (https://www.ncbi.nlm.nih.gov/pubmed/28632164) Guess where neuroglobin shows up besides in the brain? In the stomach and the small intestine! (https://www.ncbi.nlm.nih.gov/pubmed/20828399) The two body regions where I've been observing molybdenum to have an effect on mysterious illnesses--nausea/vomiting and migraines--are also places where an unknown H2S catabolic pathway appears to be occurring. I look forward to more research on neuroglobin's interaction with H2S.

* I love Poland. Lots of easily-utilized glycine betaine in the national diet, and cutting edge research in very interesting fields.

(Disclaimer: I do not prescribe the use of pharmaceutical drugs in any way. I am not a physician, and I reject out of hand any attempt to hold me liable for what boils down to a discussion of food. Any use of a molybdenum supplement should be prudent and guided by the tested tolerable upper intake levels for its usage (see http://lpi.oregonstate.edu/mic/minerals/molybdenum for those limits). Any use of an isolated molybdenum supplement during pregnancy should be under the direction of a medical professional as such supplements have apparently not been tested during pregnancy.)