Monday, May 4, 2020

A preliminary finding that highlights the important role of interleukin-6 in causing COVID-19 symptoms

A few days ago, researchers out of China announced some good news about their preliminary trials of tocilizumab, an interleukin-6 (IL-6) blocker used to treat arthritis:

The drug is a monoclonal antibody -- a cloned immune cell -- that is intended to bind to interleukin-6, or IL-6, a type of cytokine protein research suggests is part of an overactive immune response that causes serious illness in some of those infected with the new coronavirus.
By binding to IL-6, the researchers said, tocilizumab effectively works to disrupt this immune response, allowing patients to recover.
***
After treatment with tocilizumab, all patients' body temperatures returned to normal on the first day and remained stable thereafter. Within five days of treatment, 15 patients were able to reduce oxygen intake, and lung lesions were resolved in 19 patients after treatment, the study's authors wrote.
All participants were discharged between 10 and 31 days after treatment, and no side effects were reported.

https://www.upi.com/Health_News/2020/04/30/Monoclonal-antibody-used-for-arthritis-may-help-severe-COVID-19-study-suggests/1791588189875 Yale Health System is now recommending tocilizumab as the second-line treatment (right after hydroxychloroquine) for COVID-19 cases.

Guess what else inhibits IL-6 and is used for arthritis? Yes, glucosamine. Which I've been trying, with little effect, to tell people about as a potential preventive for pneumonia for over two years (see https://petticoatgovernment.blogspot.com/2018/02/glucosamine-to-protect-cartilage-during.html and https://youtu.be/JnN_OL1J8Vw).

These past three months have been extraordinarily stressful as I've watched evidence for my cartilage damage-pneumonia hypothesis mount in connection with this new virus amidst a relentless death toll that has hit my country and a former home in Ecuador especially hard. I was not able to get this idea to a wider audience (my blog is quite obscure) because I am hampered by a lack of professional connections in medical research fields. I have decided to seek a degree in an appropriate field, for being a "lawyer-housewife who is good at research and math and knows regional cuisines" is not sufficient to allow me effectively to spread information about my discoveries.

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